PROVIRID - Herbal Remedy for HIV/AIDS

PROVIRID represents a promising research initiative addressing one of the most significant public health challenges in sub-Saharan Africa. By exploring indigenous medicinal plants of Eastern Uganda for their potential as Latency Reversing Agents (LRAs), this research aims to develop locally relevant therapeutic innovations for HIV/AIDS. The project contributes to the global search for an HIV cure while promoting the utilization of Uganda's rich biodiversity for health solutions.

Problem Statement

HIV/AIDS remains a major public health challenge in sub-Saharan Africa. Although Highly Active Antiretroviral Therapy (HAART) has significantly improved the quality of life and extended the life expectancy of people living with HIV/AIDS, the disease still has no definitive cure and an effective vaccine remains unavailable. Hidden viral reservoirs continue to pose a significant challenge to complete eradication of the virus.

Project Status
Under Development / Research
Description

HIV/AIDS remains a major public health challenge in sub-Saharan Africa. Although Highly Active Antiretroviral Therapy (HAART) has significantly improved the quality of life and extended the life expectancy of people living with HIV/AIDS, the disease still has no definitive cure and an effective vaccine remains unavailable. One promising area of research is the use of Latency Reversing Agents (LRAs), which are designed to target hidden viral reservoirs. Prostratin, a naturally occurring compound, is one such LRA and has previously been isolated from plants found in the temperate regions of the Western world. In response to the need for locally relevant therapeutic innovations, PROVIRID has been developed as a herbal remedy derived from indigenous medicinal plants of Eastern Uganda.

Innovation / Solution

A herbal remedy derived from indigenous medicinal plants of Eastern Uganda that targets hidden viral reservoirs through Latency Reversing Agents (LRAs), offering a locally relevant therapeutic innovation for HIV/AIDS management and potential cure.

Key Features

• Derived from indigenous medicinal plants of Eastern Uganda
• Targets hidden viral reservoirs through Latency Reversing Agents (LRAs)
• Locally relevant therapeutic innovation
• Focuses on HIV/AIDS management and potential cure
• Utilizes naturally occurring compounds similar to Prostratin
• Addresses the challenge of viral latency

Associated Programme
PhD in Chemistry; PhD in Natural Resource and Environmental Sciences
Location / Campus
Faculty of Science and Education; Natural Products Research and Innovation Centre
Team Leader Name
Dr. Joseph Hokello
Team Leader Photo
Dr. Joseph Hokello
Target Beneficiaries

People living with HIV/AIDS in Uganda and sub-Saharan Africa; Healthcare providers; HIV/AIDS research community; Public health systems

Project Image
PROVIRID - Herbal Remedy for HIV/AIDS